GBI – Genera Biosystems Ltd.

Advanced Molecular Diagnostic Systems – Multiplex qPCR

Recombinant Human CD200 (C-6HIS)

Product overview

Company name: Bon Opus Biosciences

Product name: Recombinant Human OX-2 / MOX1 / CD200 (C-6His)

Catalog: C311

Quantity: 10 ug; 50 ug; 500 ug; 1 mg

Price: 80 USD

Type: recombinant protein

Collection: Recombinant Proteins

SKU: C311-10ug

Accession number: P41217

Background:

CD200 is a transmembrane immunoregulatory protein that belongs to the immunoglobulin superfamily. It contains an Ig-like domain like V and an Ig-like domain like C2 in its extracellular domain. CD200 is widely expressed but not ubiquitous. Its receptor (CD200R) is mainly restricted to mast cells, basophils, macrophages, and dendritic cells, suggesting that myeloid cell regulation is the main function of CD200. CD200 and CD200R associate through their respective N-terminal Ig-like domains. In myeloid cells, CD200R initiates inhibitory signals after receptor-ligand contact. In T cells, CD200 functions as an independent costimulatory molecule of the CD28 pathway. Furthermore, CD200 also plays an important role in preventing graft rejection, autoimmune diseases, and miscarriages.

Expression: human cells

Packaging: Ambient

Formulation: Lyophilized from a 0.2 ┬Ám filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Alternative names: Membrane glycoprotein OX-2, CD200, MOX1, MOX2

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