GBI – Genera Biosystems Ltd.

Advanced Molecular Diagnostic Systems – Multiplex qPCR

Peak pressure tapping atomic pressure microscopy for advancing cell and molecular biology

The appearance of atomic pressure microscopy (AFM) supplies an thrilling device to detect molecular and mobile behaviors below aqueous circumstances. AFM is ready to not solely visualize the floor topography of the specimens, but in addition can quantify the mechanical properties of the specimens by pressure spectroscopy assay. However, integrating AFM topographic imaging with pressure spectroscopy assay has lengthy been restricted because of...

Clinical application and reflection of molecular biology technology in the tertiary prevention of birth defects

Genetic components are the principle causes in prevalence of delivery defects. With deep analysis within the subject of genomics and software of molecular biology expertise, the provider standing, fetal genetic variation and postpartum screening are respectively detected from pre-pregnancy, being pregnant and post-natal screening (earlier than onset of illness) underneath excellent three-level prevention and management system for delivery...

Connecting chemistry and biology through molecular descriptors

By means of the illustration of small molecule buildings as numerical descriptors and the exploitation of the similarity precept, chemoinformatics has made paramount contributions to drug discovery, from unveiling mechanisms of motion and repurposing authorised medicine to de novo crafting of molecules with desired properties and tailor-made targets. But, the inherent complexity of organic programs has fostered the implementation of large-scale...

Systems biology approaches to unravel the molecular and genetic architecture of Alzheimer’s disease and related tauopathies

Over time, genetic research have recognized a number of genetic danger variants related to neurodegenerative problems and helped reveal new organic pathways and genes of curiosity. Nevertheless, genetic danger variants generally reside in non-coding areas and should regulate distant genes reasonably than the closest gene, in addition to a gene's interplay companions in organic networks. Methods biology and practical genomics approaches present...

Molecular biology of autoinflammatory diseases

The lengthy battle between people and varied bodily, chemical, and organic insults that trigger cell damage (e.g., merchandise of tissue harm, metabolites, and/or infections) have led to the evolution of assorted adaptive responses. These responses are triggered by recognition of damage-associated molecular patterns (DAMPs) and/or pathogen-associated molecular patterns (PAMPs), normally by cells of the innate immune system. DAMPs and PAMPs are...

fd-rapid-timmstain

Timm's silver sulfide method has hitherto been considered a very sensitive technique for demonstrating metal ions, particularly zinc, in the central nervous system. The principle of this technique is that the metals in the tissue can be histochemically transformed into metal sulphides. Subsequently, metal sulfides catalyze the reduction of silver ions by a reducing agent to metal grains that are visible under an optical or electron microscope....

hspCas9-RT-PCR Primer Set

Overview Confirm Cas9 mRNA expression With our ready-to-use Cas9 RT-PCR primer set, you can quickly and easily confirm Cas9 expression in cells or in vitro transcription assays. The amplicon for Game 1 is 219 bp and the amplicon for Game 2 2 is 122 bp. These primer sets allow the detection of nuclease Cas9, Nickase Cas9 and double mutant Cas9 at the messenger level. The primer sets are compatible with the expression of Cas9 mRNA from any SBI...

Recombinant Cyno NKG2A & CD94 Heterodimer

Product name NKG2A and CD94 heterodimer (KLRC1), recombinant protein Full Product Name Recombinant human NKG2A and CD94 heterodimeric protein (N-8His and N-DYKDDDDK) Product synonym names Heterodimer NKG2A and CD94; Heterodimer KLRC1 and CD94; CD159A and KLRD1 heterodimer Product gene name Recombinant protein KLRC1 3D structure ModBase 3D Structure for P26715 Host: Human cells Purity / Purification 95% as determined by reducing SDS-PAGE. Shape /...

GelGreen Nucleic Acid Stain 10000X DMSO

Overview Catalogue Number: SCT124 Description: GelGreen Nucleic Acid Stain 10000X DMSO General Description GelGreen is a sensitive, stable and environmentally safe green fluorescent nucleic acid stain specifically designed for gel staining. GelGreen has a UV absorption between 250 nm and 300 nm and a strong absorption peak centred around 500 nm. Therefore, GelGreen is compatible with a 254nm UV transilluminator or a gel reader equipped with...